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Dipyridamole-Brand names: Attia, Ofcram, Persantin, Persantin Retard, Trolactin

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  1. 关于二吡啶胺
  2. 关键事实
  3. 谁能也不能服用二吡啶胺
  4. How and when to take dipyridamole
  5. 副作用
  6. How to cope with side effects of dipyridamole
  7. 怀孕和哺乳
  8. 警告其他药物
  9. Common questions about dipyridamole

1.关于二吡啶胺

二吡啶胺是一种抗血小板药物。它可以防止一种血细胞(血小板)粘在一起并形成危险的血块。

如果您患有二吡啶胺的风险增加,则有助于防止血凝块。如果您有或曾经有:您的风险更高:

Dipyridamole仅在处方中可用。

它作为平板电脑和缓释(称为“修饰释放”)胶囊的出现。如果您发现很难吞咽片剂或胶囊,也可以作为液体使用。

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2.关键事实

  • The main side effects of dipyridamole are feeling or being sick, headaches and diarrhoea.
  • You can drink alcohol with dipyridamole. However, do not drink too much while taking this medicine. It can make you dizzy or lightheaded.
  • 您的医生可能会单独或每天开处方二吡啶胺低剂量阿司匹林.
  • 一些药物含有二吡啶胺和低剂量阿司匹林(品牌Molita)的组合。

3.谁可以也不能服用二吡啶胺

18岁及18岁以上的成年人可以采取双吡啶胺,以防止中风和心脏瓣膜置换手术后。

It's sometimes prescribed for children to treat a rare condition called川崎病or prevent blood clots after heart surgery.

二吡啶胺不适合某些人。为了确保这种药对您安全,请告诉您的医生,如果您:

4.如何以及何时服用二吡啶胺

How much dipyridamole you take depends on what form you have been prescribed. Always follow your doctor's instructions.

Dosage

慢速释放胶囊的通常剂量为200mg,每天服用两次。

片剂和液体的通常剂量为300毫克至600mg,每天服用3或4次。

If the doctor prescribes it for your child, they usually need to take it 2 or 3 times a day. The doctor will use your child's weight to work out the right dose.

如何服用缓慢释放的胶囊

它们在几个小时内缓慢释放您体内的药物。通常,您在早晨将1胶囊和1个胶囊在晚上取1胶囊。

Take your capsules with or shortly after a meal. Swallow them whole with a drink of water. Do not crush or chew them.

Capsules are not prescribed for children.

如何服用平板电脑或液体

您的医生会告诉您是否每天服用3或4次。每天同时服用前吃饭。用一杯水吞下平板电脑。

Dipyridamole液体带有注射器或勺子,以帮助您或您的孩子服用适当的量。如果您没有注射器或勺子,请向您的药剂师索取一个。请勿使用厨房茶匙,因为它不会给您适当的数量。

如果我忘了接受该怎么办?

If you forget to take dipyridamole, take it as soon as you remember, unless it's nearly time for your next dose. In this case, skip the missed dose and take the next one at the usual time.

Do not take a double dose to make up for a forgotten dose.

如果您经常忘记剂量,则可能有助于设置警报以提醒您。您也可以向您的药剂师询问有关记住药物的其他方法的建议。

What if I take too much?

服用1或2剂的剂量不太可能伤害您。但是,可能导致过量服用的二吡啶胺的数量因人而异。

Urgent advice:请致电111以获取建议:

您服用过多的二吡啶胺,并且有任何症状,包括:

  • 胸部的心率更快或疼痛 - 这些可能是心脏问题的迹象
  • 感到头晕或头晕,尤其是当您站起来或迅速坐起来时
  • shortness of breath, wheezing and tightening of the chest

Go to111.nhs.ukor call111

Call111如果您要问一个5岁以下的孩子。

如果您需要去医院,请不要开车。让其他人开车或打电话给救护车。

Take the dipyridamole packet or leaflet inside it plus any remaining medicine with you.

5. Side effects

像所有药物一样,二吡啶胺会引起副作用,尽管并非每个人都得到了副作用。

Common side effects

These common side effects happen in more than 1 in 100 people. Talk to your doctor or pharmacist if these side effects bother you or do not go away:

  • feeling sick
  • diarrhoea and being sick
  • 头痛
  • 感到头晕
  • feeling hot and flushed

Serious side effects

严重的副作用很少见,在不到1,000人中不到1人。

需要立即采取行动:Call 999 now if:

  • 您的胸部疼痛,呼吸急促或快速心跳

严重的过敏反应

在极少数情况下,二吡啶胺会引起严重的过敏反应(过敏反应)。

需要立即采取行动:请致电999或立即访问A&E,如果:
  • 您会得到皮疹,可能包括发痒,红色,肿胀,起泡或剥皮
  • you're wheezing
  • 你的胸部或喉咙紧绷
  • you have trouble breathing or talking
  • 你的嘴,脸,嘴唇,舌头或喉咙开始肿胀

您可能会有严重的过敏反应,可能需要在医院立即治疗。

这些并不是二吡啶胺的所有副作用。有关完整列表,请参阅您的药品包中的传单。

Information:

You can report any suspected side effect using the Yellow Card safety scheme.

访问黄牌以获取更多信息.

6.如何应对二吡啶胺的副作用

该怎么办:

  • feeling sick- 尝试在用餐或小吃后服用平板电脑。如果您不吃丰富或辛辣的食物,也可能会有所帮助。
  • diarrhoea and being sick- 在小便时喝大量的水。如果您有迹象,请与药剂师交谈dehydration,例如撒尿比平时少或黑暗,淡淡的小便。不要服用任何其他药物来治疗腹泻或呕吐,而无需与药剂师或医生交谈。
  • 头痛– make sure you rest and drink plenty of fluids. Do not drink too much alcohol. Ask your pharmacist to recommend a painkiller. Talk to your doctor if the headaches are severe or last longer than a week.
  • 感到头晕- 如果二吡啶氨甲站立时会让您感到头晕,请尝试慢慢起床或保持坐下,直到感觉好转为止。如果您开始感到头晕,请躺下,以免晕倒,然后坐一会儿,直到感觉好转。如果您感到头晕或有点摇晃,请勿驾驶,骑自行车或使用工具或机械。
  • feeling hot and flushed– try cutting down on coffee, tea and alcohol. It might help to keep the room cool and use a fan. You could also spray your face with cool water or sip cold or iced drinks. The flushing should go away after a few days. If it does not, or if it's causing you problems, contact your doctor.

7.怀孕和母乳喂养

Dipyridamole and pregnancy

Dipyridamole is not often used in pregnancy. This is because there is little information about how the medicine may affect your baby. However, your doctor may advise you to take it if they think the benefits of taking the medicine outweigh any risks.

如果您想怀孕或已经怀孕,请与您的医生讨论服用二吡啶胺的好处和可能的伤害。这些取决于您怀孕了多少周以及您需要服用它的原因。怀孕时可能会有其他药物更适合您。

二吡啶胺和母乳喂养

只有在医生建议您的情况下母乳喂养时才服用二吡啶胺。

It's not known how much dipyridamole gets into breast milk, but it's likely to be a small amount.

If your doctor says it is OK for you to keep taking dipyridamole, then monitor your baby for any possible side effects, such as bruises or bleeding easily. However, it's unlikely that dipyridamole will cause any side effects in your baby.

如果您在母乳喂养时对婴儿有任何疑问,请与您的医生,助产士或健康访客交谈。

Non-urgent advice:告诉您的医生,如果您是:

  • 试图怀孕
  • 哺乳

8.警告其他药物

一些药物会影响二吡啶胺的工作方式。

Tell your doctor if you're taking these medicines before you start taking dipyridamole:

Taking dipyridamole with everyday painkillers

你可以采取扑热息痛together with dipyridamole if you need a painkiller.

Do not take阿司匹林缓解疼痛(300mg tablets) oribuprofen当您服用Dipyridamole时,除非医生说可以。他们增加了出血的风险。

为了防止血块,您的医生可能会开处方每天的低剂量阿司匹林(75mg片剂)与二吡啶胺一起服用。

服用二吡啶胺用消化不良药物

一些消化不良药物,例如奥美拉唑,可以减少二吡啶胺的作用。如果您将二吡啶胺作为平板电脑或液体,这很重要,但是如果您要服用胶囊,这不是问题。

If you need to take indigestion medicines, do not take them at the same time of day as dipyridamole tablets or liquid. Take them 2 to 3 hours before or after your dose of dipyridamole.

将二吡啶胺与草药和补品混合

There might be a problem with taking some herbal remedies and supplements with dipyridamole, especially ones that can affect your blood, such as ginkgo.

Important:医学安全

告诉您的医生或药剂师,您是否正在服用其他药物,包括草药,维生素或补充剂。

9.关于二吡啶胺的常见问题

How does dipyridamole work?

Dipyridamole slows the blood's clotting action by making platelets less sticky.

血小板是粘在一起并阻塞血管中的切割和断裂的血细胞。

However, in people at risk of心脏病发作or中风,血小板可以在已经狭窄的血管内部粘在一起以形成凝块。凝块可以阻止血液流向心脏或大脑,并引起心脏病发作或中风。

If you take it every day, dipyridamole stops platelets from clumping together to form unwanted blood clots. This helps to prevent heart attacks and strokes.

工作需要多长时间?

Dipyridamole works within 2 hours of taking it.

When will I feel better?

开始服用Dipyridamole后,您可能没有任何不同。但是,这并不意味着药物不起作用。

Carry on taking dipyridamole even if you feel well, as you'll still be getting the benefits.

How long will I take it for?

You will usually need to take dipyridamole for the rest of your life.

长时间服用安全吗?

Dipyridamole is generally safe to take for a long time. In fact, it works best if you take it for many months or years.

如果我停止服用会发生什么?

Do not stop taking dipyridamole without talking to your doctor.

如果您停止服用二吡啶胺,您的血液通常会以前的速度凝结,通常在停止药物后的2天内。这意味着您可能会增加患心脏病或中风等严重问题的风险。

Are there any other similar medicines?

Other antiplatelet medicines include低剂量阿司匹林,clopidogrelticagrelor.

Anticoagulant medicines such asapixaban,达比加特兰,edoxaban,利瓦沙班华法林还规定了有助于防止血凝块的规定。

Not all medicines that prevent blood clots are suitable for everyone. Talk to your doctor or pharmacist to find out why you've been recommended a particular medicine.

我可以喝酒吗?

是的,只要您坚持每周不超过14个单位的男性酒精准则,就可以喝酒时喝酒。一杯标准的葡萄酒(175毫升)为2个单位。一品脱的啤酒或啤酒通常是2至3个单位。

酒精和二吡啶胺都可以降低您的血压。他们在一起会让您感到头晕或头晕。如果您发现二吡啶胺会让您感到头晕,最好停止喝酒。

我需要避免任何食物或饮料吗?

Apart from limiting your alcohol intake, you can eat and drink normally while taking dipyridamole.

我需要在手术前停止二吡啶胺吗?

Because of the risk of bleeding, you may need to stop taking dipyridamole a few days before you have an operation. Tell the surgeon in advance that you are taking dipyridamole.

我可以接种疫苗吗?

是的,您可以在服用二吡啶胺时进行疫苗接种。

Will it affect my contraception or fertility?

Dipyridamole不影响任何类型的避孕药,包括混合药紧急避孕.

If dipyridamole makes you vomit, your contraceptive pills may not protect you from pregnancy. Look on the pill packet to find out what to do.

如果您服用药丸并且生病该怎么办.

服用二吡啶胺对雄性或女性生育没有任何影响。

这会影响我的性生活吗?

二吡啶胺不会影响您的性生活。

Can I drive or ride a bike?

Most people can drive or ride a bike while taking dipyridamole. However, if dipyridamole makes you feel dizzy, do not drive, ride a bike or operate tools or machinery until the dizziness is gone.

生活方式的改变可以帮助改善我的总体健康状况吗?

如果您被处方二吡啶胺,也可以通过改变一些关键的生活方式来改善健康。

  • 戒烟 - 吸烟会增加您的心率和血压。戒烟会降低您患心脏病或中风的风险。尽量避免二手烟。
  • Cut down on alcohol – it's a good idea not to drink more than 14 units of alcohol a week.
  • Get more exercise – regular exercise keeps your heart and blood vessels in good condition. It does not need to be too energetic – walking every day can help.
  • 吃得好 - 旨在吃包括大量水果和蔬菜,全麦,无脂或低脂乳制品以及瘦蛋白质的饮食。最好遵循这些技巧,以减少盐饮食。每天不超过6克盐。
  • 管理压力- 当您焦虑或沮丧时,您的心脏跳动更快,您的呼吸更加严重,血压通常会升高。这增加了您患心脏病和中风的风险。寻找减少生活压力的方法。为了让您的心脏休息,请尝试在可能的情况下小睡或抬起脚。与朋友和家人共度时光,以社交并帮助减轻压力。
  • 疫苗接种- 如果您患有心脏病,建议您有一个流感疫苗every year and apneumococcal vaccine每5年一次。向您的医生询问这些疫苗。您可以在NHS上免费提供它们。

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