1. About co-codaprin
Co-codaprin is a mixture of 2 different painkillers:aspirin和codeine。
它用于治疗疼痛和痛苦，包括headaches, muscular pain,migraine和toothache。 It can also be used to treat the symptoms of感冒和flu。
阿司匹林属于一组名为non-steroidal anti-inflammatory drugs (NSAIDS）。
可待因属于一组称为阿片类药物的药物。它会影响中枢神经系统和大脑中的疼痛受体，以阻止疼痛信号到身体的其余部分。
通常是在日常止痛药时服用的paracetamol,ibuprofen和aspirin alone, have not worked.
This medicine comes as tablets. It's available on prescription. Co-codaprin is available without a prescription, but only from a pharmacy.
2.关键事实
- 联合二快乐是阿司匹林和可待因的另一个名称。
- 如果您从药房购买联合二快乐，并且三天后您的疼痛不会更好，请务必向医生提供有关持续缓解疼痛的建议。
- It's possible to become addicted to the codeine in this medicine if you take it for too long. Only take it when you need it for pain relief.
- It's best to take co-codaprin with or just after eating food. You'll be less likely to get mild indigestion or stomach pain. These are common side effects of co-codaprin.
- 除非他们的医生开处方，否则切勿给16岁以下的儿童共同二p。这是因为它含有阿司匹林，这可能会对儿童产生严重的副作用。
3. Who can and cannot take co-codaprin
Who can take co-codaprin
Most people aged 16 years old and over can safely take co-codaprin. But co-codaprin is not suitable for some people.
阿司匹林在共同二磷蛋白和雷耶综合症in children. Reye's syndrome is a very rare condition that can cause serious liver and brain damage.
请勿将18岁以下的任何人兼容扁桃体或腺样体进行治疗阻塞性睡眠呼吸暂停。
重要的：Children under 16 years
除非他们的医生开处方，否则切勿给16岁以下的儿童共同二p。
Who may not be able to take co-codaprin
为了确保联合二快乐对您安全，请告诉您的医生或药剂师：
- 曾经有一个n allergy toaspirin或者codeine(or similar painkillers such asibuprofen和morphine)
- 有surgery planned – you'll need to stop taking aspirin several days before you have surgery (including dental surgery)
- 曾经有一个blood clotting problem
- 曾经有一个胃溃疡
- 有indigestion
- 有recently had astroke，尽管这取决于您所拥有的中风（您的医生Mayrecommend您接受低剂量阿司匹林 to prevent another one)
- 有low blood pressure (hypotension)或者高血压（高血压）
- 有asthma或者lung disease
- 有liver or kidney problems
- 有痛风 – it can get worse for some people who take aspirin
- 得到heavy periods– they can get heavier with aspirin
- 头部受伤或导致癫痫发作或适合的状况
- 有adrenal gland problems or an underactive thyroid gland
- 对酒精或毒品成瘾
- 有胆结石
- 有an前列腺肥大
- 有myasthenia gravis(a rare condition that causes muscle weakness)
- 有症状ulcerative colitis(a bowel condition)
- 有glucose-6-phosphate dehydrogenase (G6PD) deficiency
- 怀孕，试图怀孕或想母乳喂养
4.如何以及何时服用共二吡啶
Follow the instructions that come with your medicine. This is particularly important because the codeine in co-codaprin can be addictive.
Dosage and strength
The strength of co-codaprin appears as 2 numbers on the packet, for example, as 8/400. This means it contains 8mg of codeine and 400mg of aspirin.
成人的通常剂量（18岁以上）为1或2个二碳二快乐片，在24小时内最多4次。
始终在剂量之间至少留4小时。
The maximum dose is 8 tablets in 24 hours.
The usual dose for teenagers aged 16 to 18 years old is the same. They should not have co-codaprin, however, if they have had their tonsils or adenoids taken out to treat obstructive sleep apnoea.
重要的
Do not take more than 8 co-codaprin tablets in 24 hours.
How to take it
Swallow co-codaprin tablets whole with a drink of water. It's best to take them with or just after food.
How long to take it for
如果您从药房购买了联合二快乐，请不要使用超过3天。如果您仍然有疼痛，请与您的药剂师或医生交谈。重要的是要向他们提供有关缓解疼痛的建议。
If your doctor has prescribed co-codaprin for you, follow their advice carefully.
If you take too much
如果您在一次场合服用1或2片二磷脂，则不太可能有害。
If this happens, wait at least 24 hours before you take any more. Taking more than this can be dangerous.
如果您错误地犯了太多的二快乐，您可能会感到非常困倦，生病或头晕。您可能还会发现很难呼吸。
在严重的情况下，您可能会失去知觉，可能需要在医院进行紧急治疗。
Urgent advice:立即联系111以获取建议，如果：
- 您服用的比通常的二碳酸二捷克剂量更多，感到困倦，生病或头晕目眩
Go to111.nhs.uk或者call111
If you need to go toA&E不要开车自己。让其他人开车或打电话给救护车。
Take the co-codaprin packet, or the leaflet inside it, plus any remaining medicine with you.
需要立即采取行动：Call 999 or go to A&E now if:
- 您服用过多的共同二快乐，呼吸困难
5. Taking co-codaprin with other painkillers
可以安全地与paracetamol。
Do not take co-codaprin with any other medicines that containcodeine。
也不要与任何其他非甾体类抗炎药一起服用（NSAIDS) includingaspirin,ibuprofen或者萘普生。如果您一起使用NSAID，它可能会增加您获得副作用的机会stomach ache或流血。
These painkillers are often included in medicines you can buy from pharmacies. For example, Nurofen or Nurofen Plus, or cough and cold remedies such as Nurofen Cold & Flu or Beechams Powders.
重要的
Before taking any other medicines, check the label to see if they contain codeine, aspirin, ibuprofen or other NSAIDs.
6. Side effects
Like all medicines, co-codaprin can cause side effects, although not everyone gets them. Many people have no side effects or only minor ones.
Common side effects
这些副作用发生在100人中有1人中发生。告诉您的医生，这些副作用是否困扰您或不离开：
- mildindigestion
- feeling or being sick (nausea or vomiting)
- 便秘
- 感到困倦
- bleeding more easily than normal – because aspirin thins your blood, it can sometimes make you bleed more easily (for example, you may get流鼻血, bruise more easily and, if you cut yourself, the bleeding may take longer than normal to stop)
- dizziness andvertigo（一种旋转的感觉）
- headaches
Serious side effects
严重的副作用很少见，在100人中不到1人中发生。
如果有的话，请立即与医生联系：
- a change in your normal heart rate (slower or faster) and you feel dizzy or very tired – these can be signs of a heart problem
- a fit or seizure
- difficulty breathing or short, shallow breathing
- 肌肉的僵硬
- feeling faint when you stand up or sit quickly – this can be a sign oflow blood pressure
- coughing up blood or blood in your pee, poo or vomit
- dark pee or the whites of your eyes turn yellow – this can be a sign of liver problems
- 您的手和脚疼痛的关节 - 这可能是血液中高水平尿酸的标志
- swollen hands or feet – this can be a sign of a build-up of fluid in your body
严重的过敏反应
在极少数情况下，可能会有严重的过敏反应（过敏反应) to co-codaprin.
需要立即采取行动：Call 999 or go to A&E now if:
- you get a skin rash that may include itchy, red, swollen, blistered or peeling skin
- you're wheezing
- you get tightness in the chest or throat
- you have trouble breathing or talking
- 你的嘴，脸，嘴唇，舌头或喉咙开始肿胀
您可能会有严重的过敏反应，可能需要在医院立即治疗。
These are not all the side effects of co-codaprin. For a full list, see the leaflet inside your medicine packet.
7. How to cope with side effects of co-codaprin
该怎么办：
- mild indigestion- 用食物或饭后服用联合二邻糖。如果消化不良仍然没有消失，则可能表明二快乐会导致胃溃疡。 Talk to your doctor, as they may prescribe something to protect your stomach or switch you to a different medicine.
- feeling or being sick (nausea or vomiting)– take co-codaprin with or just after a meal or snack. Feelings of sickness should normally wear off after a few days. Talk to your doctor about taking an anti-sickness medicine if it carries on for longer.
- 便秘- 将更多的纤维纳入您的饮食中，例如新鲜水果，蔬菜和谷物。每天尝试喝几杯水或其他非酒精液体。如果可以的话，它也可能有助于提高您的锻炼水平。
- 感到困倦或疲倦- 如果您有这种感觉，请勿开车，骑自行车或使用工具或机械。不要喝任何酒精，因为这会让您感到疲倦。
- bleeding more easily than normal- 在进行可能造成伤害或削减的活动时要小心，因为任何出血都可能比平常更长。
- dizziness and vertigo- 如果您感到头晕或不稳定，请停止所做的事情，坐下或躺下，直到感觉好转为止。如果您感到头晕目眩，请勿开车，骑自行车或使用工具或机械。不要喝酒，因为它会让您感到更糟。
- headaches– make sure you rest and drink plenty of fluids. It's best not to drink too much alcohol. Talk to your doctor if the headaches last longer than a week or are severe.
8. Pregnancy and breastfeeding
Co-codaprin and pregnancy
怀孕期间不建议使用二快乐。您可以服用更安全的药物。向您的医生或药剂师咨询建议。
对于大多数女性，paracetamol是怀孕的最佳止痛药。
Co-codaprin and breastfeeding
母乳喂养时不建议使用二快乐。
对于大多数女性来说，最好服用paracetamol或者ibuprofenfor pain or a high temperature while you're breastfeeding.
Non-urgent advice:告诉您的医生，如果您是：
- 试图怀孕
- 孕
- 哺乳
For more information about how pain relief can help you during pregnancy,访问怀孕（BUMP）网站上最佳使用药物。
9.警告其他药物
有些药物会影响共同二磷杆菌的方式。联合二邻生会影响某些药物的工作方式。
告诉您的医生是否服用其他药物，特别是：
- 有助于防止血凝块的药物，例如华法林和clopidogrel
- 药物疼痛和肿胀（炎症），例如ibuprofen和萘普生
- 安眠药，antidepressants或者lithium（药物前洞健康问题）新利 首页
- medicines to stop you feeling or being sick, such asDomperidone或者甲氧氯普胺
- 治疗感染的药物，特别是利福平和环丙沙星
- epilepsy medicines
- 在移植后，药物预防器官排斥，此类腹孢菌素和他克莫司
- steroids, such asprednisolone
- 治疗高血压的药物，例如ramipril
- diuretics (medicines to make you pee more), such as弯曲的甲氮化氮杂和furosemide
- digoxin, a medicine for heart problems
- 乙酰唑胺，对于一个称为青光眼的眼睛问题
- methotrexate, a medicine used to calm your immune system and treat some types of cancer
- diabetes medicines, such asgliclazide
- 抗组胺药使您感到昏昏欲睡，就像chlorphenamine
将共二吡啶与草药和补品混合
It's not possible to say thatherbal remedies或者supplements are safe to take with co-codaprin.
They are not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.
重要的：医学安全
告诉您的医生或药剂师，您是否正在服用其他药物，包括草药，维生素或补充剂。
10.关于联合二吡啶的常见问题
联合二快乐如何工作？
Co-codaprin containsaspirin和codeine。These 2 painkillers work in different ways to relieve pain.
阿司匹林属于一组名为non-steroidal anti-inflammatory drugs (NSAIDs)。
If you have been hurt or have an infection, your body makes hormones called prostaglandins. The prostaglandins cause swelling and sometimes a high temperature, and they send pain signals to the brain.
这是身体对伤害自然反应的一部分。肿胀和高温可以帮助您的身体愈合。
Aspirin stops your body making prostaglandins, and this reduces the pain, swelling and high temperature.
可待因属于一组称为阿片类药物的药物。它会影响中枢神经系统和大脑中的疼痛受体，以阻止疼痛信号到身体的其余部分。
当可待因阻止疼痛受体时，还有其他不必要的作用（例如，缓慢而浅的呼吸）。它也可以减慢消化，这就是为什么可待因会导致便秘的原因。
When will I feel better?
Co-codaprin takes up to 1 hour to work. It keeps on working for about 4 hours.
我可以花多长时间？
If you've bought co-codaprin from a pharmacy, do not use it for more than 3 days. If your pain has not gone away, talk to your pharmacist or doctor.
If your doctor has prescribed co-codaprin for you, follow their advice.
Depending on why you're taking it, you may need to take it for a few days or weeks at most – for example, if you're in pain after an injury or operation.
如果您不确定需要多长时间服用联合二快乐，请与您的药剂师或医生交谈。
联合二快乐成瘾性吗？
如果您长时间定期服用二哌林，您可能会沉迷于其中的可待因。
You're unlikely to become addicted if you follow your doctor's advice carefully about how long to take it for.
If you have bought co-codaprin at a pharmacy, follow the instructions that come with the medicine and only take it for up to 3 days at a time. If your pain is not better after 3 days, it's important to ask your doctor for advice about ongoing pain relief.
How will I know if I'm addicted?
如果您沉迷于共同二快乐，您可能会发现很难停止服用它，或者觉得您需要比必要的更频繁地服用它。
如果您突然停止服用，您可能会患有戒断症状。这些包括感到烦躁，感到焦虑，颤抖或出汗。
Talk to your doctor if you're worried about addiction.
Can I take co-codaprin for a long time?
It's not usually recommended to take co-codaprin that you have bought from a pharmacy for longer than 3 days.
最好以最短的时间服用最低剂量。
That way there's less chance that you'll get unwanted side effects like stomach ache.
If you need to take co-codaprin for longer than 3 days, ask your doctor or pharmacist for advice.
二快乐二快乐是否比扑热息痛或布洛芬更好地缓解疼痛？
Not necessarily.Paracetamol,ibuprofen,aspirin和codeine都是有效的止痛药。
Some painkillers work better than others for certain pains. For example, the best painkiller to ease your headache may not be the best one for your backache.
Try taking one of these painkillers before trying co-codaprin to see if it helps your pain:
- Paracetamol可以缓解大多数类型的疼痛。它通常用于轻度或中度疼痛。对于头痛，牙痛，扭伤，胃痛和神经疼痛，可能比阿司匹林更好。
- 布洛芬与阿司匹林类似的方式工作。它可用于背痛，菌株和扭伤，以及关节炎的疼痛。这也适合牙痛和时期疼痛。
- Aspirinmay be better than paracetamol for some pains, such as period pain or migraines. But if you have heavy periods, aspirin can make them heavier. Some people find aspirin better than paracetamol for back pain.
- 可待因只有仅如果仅有效，只有阿司匹林，布洛芬或扑热息痛就可以使用。这是因为它用于治疗中度至严重的疼痛 - 例如，手术或受伤后。
Can I drive or ride a bike with it?
如果共同二快乐在白天让您困倦，请不要驾驶汽车或骑自行车，使您的视力模糊或使您感到头晕，笨拙或无法集中精力或做出决定。
当您首次开始服用共同二磷蛋白时，这可能更有可能发生，但可能随时发生 - 例如，开始另一种药物时。
如果您的安全驾驶能力受到影响，则驾驶汽车是一种冒犯。决定是否安全开车是您的责任。如果您有任何疑问，请不要开车。
即使您的开车能力不受影响，警察也有权要求唾液样本检查您体内有多少二快乐。
Talk to your doctor or pharmacist if you're unsure whether it's safe for you to drive while taking co-codaprin.
我可以喝酒吗？
服用二碳二邻二邦时喝酒会刺激您的胃，使您感到更困。
最好在治疗的最初几天停止喝酒，直到您看到二氧酸二答肽如何影响您。
如果您对二吡啶二快乐感到困，请在服用时停止喝酒。
Is there any food or drink I need to avoid?
除了限制酒精外，您还可以在服用联合二碳纤维蛋白时正常饮食。
联合二快乐可以使您体重增加吗？
没有证据表明服用共二吡啶会使您体重或减肥。
会影响我的生育能力吗？
如果您要在短时间内服用联合二快乐，并且没有明确的证据表明它可以降低生育能力。
但是，如果您已经服用了很长时间，并且您担心自己的生育能力，或者您想怀孕，请与药剂师或医生交谈。
娱乐性药物会影响它吗？
如果您服用大麻，可卡因和海洛因等娱乐性药物，当您服用共同二快乐时，您更有可能在共同二快乐中获得严重的副作用。
These include breathing difficulties, heart problems, fits or seizures, and even going into a coma.
Some recreational drugs, such as cannabis, make you more likely to have side effects from the codeine. These include sleepiness and dizziness.
Taking heroin while you're on prescribed co-codaprin is especially dangerous. You're more likely to get all the side effects of the codeine in co-codaprin, including addiction.
Speak to your doctor if you think you might take recreational drugs while taking co-codaprin.